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SYNICEM™ Knee Spacer

Specifically designed to maintain joint space in your knee revisions

Specifically designed to maintain joint space in your knee revisions

Combining convenience, structural uniformity and stability, while delivering a local concentration of gentamicin.

SYNICEM knee spacers maintain articular space, limb length and ligament structures.6

  • Precision engineered for consistency and structural uniformity
  • Designed to maintain joint mobility and stability
  • Preloaded with gentamicin
  • Case-by-case flexibility and time-saving

Precision engineered for consistency and structural uniformity

Strictly controlled manufacturing conditions minimize the risk of mechanical failure by eliminating unwanted variation and ensuring the uniform shape and structural integrity of the base material.

  • Intra-operatively prepared spacers are time-consuming to make and prone to fracture.1

Designed to maintain joint mobility and stability

Designed to maintain the articular space, limb length and ligament structures after removal of the original implant.6

  • Specific left and right geometries for each knee
  • Tibial stem ensures stability of the tibial component
  • Tibial post aligns the femoral component

Preloaded with gentamicin

The spacer yields a prolonged local concentration of gentamicin while maintaining low systemic levels.6,7

Case-by-case flexibility and time-saving

A comprehensive range of sizes and styles provide case-by-case flexibility, with a reusable trial spacer tray available to ensure you select the correct size every time.6

  • No molding required

SYNICEM™ Knee Spacer products
SYNICEM™ Hip Spacer

Specifically designed to maintain joint space in your hip revisions

SYNICEM™ Shoulder Spacer

Specifically designed to maintain joint space in your shoulder revisions

References and regulatory statements

  1. Craig, A. et al., (2022). Articular spacers in two-stage revision arthroplasty for prosthetic joint infection of the hip and the knee. EFORT Open Reviews, 7, 137–152.
  2. Ocguder, A. et al., (2010). Two-stage total infected knee arthroplasty treatment with articulating cement spacer. Archives of orthopaedic and trauma surgery, 130(6), 719–725.
  3. Dunne, N. et al., (2007). In vitro study of the efficacy of acrylic bone cement loaded with supplementary amounts of gentamicin: effect on mechanical properties, antibiotic release, and biofilm formation. Acta orthopaedica, 78(6), 774–785.
  4. Hollyer, I. et al., (2023). Selecting a high-dose antibiotic-laden cement knee spacer. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 41(7), 1383–1396.
  5. Moerenhout, K. et al., (2021). Economic advantage of ‘self-made’ antibiotic-loaded spacer compared to prefabricated antibiotic-loaded spacer and spacer molds in two-staged revision arthroplasty. Acta orthopaedica Belgica, 87(3), 557–562.
  6. SYNICEM Spacers: Instructions for Use.
  7. Biocomposites, Data on file.

©2025, Biocomposites, STIMULAN are trademarks/registered trademarks of Biocomposites Ltd. Synimed and Synicem are trademarks/registered trademarks of Synergie Ingénierie Médicale S.A.R.L. All rights reserved. No unauthorized copying, reproduction, distributing or republication is allowed unless prior written permission is granted by the owner, Biocomposites Ltd.

Patents granted: GB2367552, EP 1204599 B1, US 6780391, EP 2594231 B1, US 8883063, CN ZL201210466117.X, GB2496710, EP 3058899 B1, US 10390954, US 10,588,748, CN ZL201610089710.5
Patents pending: GB1502655.2, GB1704688.9, EP 18275044.8, US 15/933936, CN 108619579A

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