Management of Osteomyelitis-Induced Massive Tibial Bone Defect by Monolateral External Fixator Combined with Antibiotics-Impregnated Calcium Sulphate: A Retrospective Study

Qin, C., et al., BioMed Research International, 2018. 2018: p. 8.

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The aim of this study was to evaluate the effect of a combined treatment protocol for 35 patients with tibial osteomyelitis. Treatment consisted of radical debridement, placement of antibiotics-impregnated calcium sulphate (STIMULAN) and monoliteral external fixation. STIMULAN was used as a carrier material for vancomycin and/or gentamicin and used to fill the debrided bone void and the medullary cavity. The mean follow-up was 33.7 months. The average bone defect length was 9.5cm, measured radiographically post-surgery. Bone union was achieved in 34/35 patient, and one reinfection observed. The most common complaint was pain which was relieved after administering oral analgesics. The abstract can be read, and the full paper can be obtained here.

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