The aim in this prospective observational study of 755 patients, was to assess the safety profile of STIMULAN when used as a carrier material for vancomycin and tobramycin in revision total knee and hip arthroplasty. Complication rates such as drainage, hypercalcaemia and heterotopic ossification were compared to those reported in literature.
The average quantity of STIMULAN used per procedure was 23.39cc with STIMULAN related complications occurring in 11.4% of operations. Drainage accounted 4.2%, HO for 1.7% and hypercalcaemia for 5.4% with normal levels returning at a maximum of 5 days postoperatively. The authors recommend that all patients are screened for contraindications, with serum calcium levels monitored both pre and post operatively.
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